Urban Air Mobility (UAM) encompasses a major role in the improvement of people´s lives and the upcoming technology of the Vertical Take Off and Landing (VTOL) systems determine the necessity of a new way to make compatible and understand all the different uses that the airspace demands altogether in this complex and interdisciplinary scenario the focus of this study is to bring the spotlight to the city of São Paulo in Brazil with its all existing nowadays complexity demonstrating the feasibility to adopt this solution in terms of demand, regulatory, site location, social acceptance, and price range accepted for the service.